7	REFERENCES

Abbott, J.G., unpublished, A summary of native submissions to the International Joint Commission since 1975. February 1998. International Joint Commission, Ottawa. 44 pp.

Agency for Toxic Substances and Disease Registry, 1988. The Nature and Extent of Lead Poisoning in Children in the United States: A Report to Congress. Atlanta, Georgia.

Ahlborg, U.G. et al., 1994. Toxic equivalency factors for dioxin-like PCBs: Report on a WHO-ECEH and IPCS consultation. Chemosphere, 28:1049-1067.

Benedict, E., 1985. Submission to Canadian Water; The State of the Resource. Rawson Academy of Aquatic Sciences Conference. Toronto. 85 pp.

Brant, Daniel, 1998. Personal communication (On the occasion of the 19^th Meeting of the SAB's Workgroup on Emerging Issues, Windsor, November 1998).

Browner, Carol M., U.S. EPA Directive of March 14, 1994. Attachment B: EPA Policy for the Administration of Environmental Programs on Indian Reservations, November 8, 1984. 4 pp.

Carpenter, D.O., K.F. Arcaro, B. Bush, W.D. Nieni, S. Pang and D.D. Vakharia, 1998. Human health and chemical mixtures: An overview. Environmental Health Perspectives. 106(Suppl. 6):1263-1270.

Centers for Disease Control, 1991. Preventing Lead Poisoning in Young Children. Atlanta, Georgia.

Cheek, A.O., P.M. Vonier, E. Oberdorster, B.C. Burow and J.A. McLachlan,1998. Environmental signaling: A biological context for endocrine disruption. Environmental Health Perspectives. 106:5-10.

Cohen, M., B. Commoner, H. Eisl, P. Bartlett, A. Dickar, C.Hill, J. Quigley and J. Rosenthal, 1995. Quantitative Estimation of the Entry of Dioxins, Furans and Hexachlorobenzene into the Great Lakes from Airborne and Waterborne Sources. Center for the Biology of Natural Systems, Queens College. Flushing, NY. 105 pp.

Colborn, T. and C. Clement, (eds.). 1992. Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Advances in Modern Environmental Toxicology. Princeton Scientific Publishing, Princeton, New Jersey. 403 pp.

Colborn, T., P. Short, and M. Gilbertson, (Eds.), 1999. Health Effects of Contemporary-Use Pesticides: The Wildlife/Human Connection. Toxicology and Industrial Health, 15:1-275.

Colborn, T., F. vom Saal, and P. Short (Eds.), 1998. Environmental Endocrine-Disrupting Chemicals: Neural, Endocrine, and Behavioral Effects. Princeton Scientific, New Jersey. 418 pp.

Cook, P.M., E.W. Zabel, and R.E. Peterson, 1997. The TCDD toxicity equivalence approach for characterizing risks for early life-stage mortality in trout. In: Chemically Induced Alterations in Functional Development and Reproduction of Fishes. Rolland, R.M., M. Gilbertson and R.E.Peterson (Eds.). Society of Environmental Toxicology and Chemistry. Tech. Pub. Series 194 pp.

Courval, J.M., J.V. DeHoog, A.D. Stein, E.M. Tay, J. He, H.E.B. Humphrey and N. Paneth, 1999. Sport-Caught Fish Consumption and Conception Delay in Licensed Michigan Anglers. Environmental Research. 80(Suppl.):183-188.

De Rosa, C.T., Z.A. Rosemond, W. Cibulas and A.P. Gilman, 1999. Research Management in the Great Lakes and St. Lawrence River Basins: Challenges and Opportunities. Environmental Research. 80:274-279.

Ecological Society of America, 1997. Human Alteration of the Global Nitrogen Cycle: Causes and Consequences. Issues in Ecology No. 1. Washington, D.C.

Epstein, P., B. Sherman, E. Spanger-Siegfried, A. Langston, S. Prasad, and B. Mckay, 1998. Marine Ecosystems: Emerging Diseases as Indicators of Change. Health, Ecological and Economic Dimensions (HEED) of Global Change Program. Year of the Ocean Special Report. Harvard Medical School, Boston, MA.

Goldey, E.S., L.S. Kehn, C. Lau, G.L. Rehnberg, and K.M. Crofton, 1995. Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone deficits in rats. Toxicol. Appl. Pharmacol., 135:77-88.

Gray, L.E., J. Ostby, R.L. Cooper and W.R. Kelce, 1999. The estrogenic and antiandrogenic pesticide methoxychlor alters the reproductive tract and behavior without affecting pituitary size or LH and prolactin secretion in male rats. Toxicology and Industrial Health, 15:37-47.

Great Lakes Commission, 1996. An agricultural profile of the Great Lakes basin: Characteristics and trends in production, land-use and environmental impacts. Prepared by Agricultural Profile Project Team. Final draft April 1996, 184 pp., plus 6 appendices, 304 pp.

Great Lakes Science Advisory Board, 1997. Priorities Report 1995-1997 to the International Joint Commission. Windsor, Ontario.

Great Lakes Water Quality Board, 1993. Legislative and Regulatory Considerations for Virtual Elimination of Persistent Toxic Substances. International Joint Commission. Windsor, Ontario, Canada. 15 pp.

Hartman, W.L., 1988. Historical changes in the major fish resources of the Great Lakes. In: Toxic Contaminants and Ecosystem Health; A Great Lakes Focus. Evans, M.S. (ed.). John Wiley & Sons, Inc., New York. pp. 103-131.

Health Canada, 1998. Endocrine Disrupters Annual Report. Prepared for Health Protection Branch by the HPB Endocrine Disrupter Committee. Ottawa, Ontario, Canada. 13 p.

Hessel, D.O. (ed.). 1997. Special Issue: Nitrogen from Mountains to Fjords. Ambio. 26:253-325.

Hoff, R.M., W.M.J. Strachan, C.W. Sweet, C.H. Chan, M. Shackleton, T.F. Bidleman, K.A. Brice, D.A. Burniston, S. Cussion, D.F. Gatz, K. Harlin, and W.H. Schroeder, 1996. Atmospheric deposition of toxic chemicals to the Great Lakes. Atmospheric Environment. 30:3505-3527, and errata 31:1585.

International Joint Commission, 1998. Ninth Biennial Report on Great Lakes Water Quality. Washington, DC and Ottawa, ON. 79 pp.

International Joint Commission, 1997. 1995-97 Priorities and Progress under the Great Lakes Water Quality Agreement. 134 pp.

International Joint Commission, 1997. The IJC and the 21^st Century. Washington and Ottawa. 50 pp.

International Joint Commission, 1994. Our Community, Our Health: Dialogue Between Science and Community. Report of the Great Lakes Science Advisory Board to the International Joint Commission. 50 pp.

International Joint Commission, 1991. Great Lakes Science Advisory Board 1991 Report to the International Joint Commission, Windsor. 126 pp.

International Joint Commission, 1990. The International Joint Commission and the Boundary Waters Treaty. Text of 1909 Treaty, IJC Rules of Procedure and Overview of IJC Activities. Washington, DC and Ottawa, Canada, 25 pp.

International Joint Commission, 1989. Report of the Great Lakes Science Advisory Board to the International Joint Commission, Windsor. 92 pp.

International Joint Commission, 1987. Great Lakes Water Quality Agreement of 1978 as amended by Protocol signed November 18, 1987. Washington and Ottawa. 64 pp.

International Joint Commission. 1996. Indicators to Evaluate Progress Under the Great Lakes Water Quality Agreement. Windsor, Ontario. 82 pp.

Jacobson, J.L., and S.W. Jacobson, 1996. Intellectual impairment in children exposed to polychlorinated biphenyls in utero. New England Journal of Medicine, 335(11):783-789.

Jacobson, J.L., and S.W. Jacobson, 1993. A four-year followup study of children born to consumers of Lake Michigan fish. J. Great Lakes Research, 19:776-783.

Jacobson, J.L., G.G. Fein, S.W. Jacobson, P.M. Schwartz and J.K. Dowler, 1985. The effect of intrauterine PCB exposure on visual recognition memory. Child Development, 56:853-860.

Jacobson, J.L., S.W. Jacobson, G.G. Fein, P.M. Schwartz, and J.K. Dowler, 1984. Prenatal exposure to an environmental toxin: A test of the multiple effects model. Developmental Psychology, 20:523-532.

Japan Chemical Industry Association, 1997. A Study on Hormone-Like (Hormone-Mimic) Effects of Exogenous Substances. Japan Chemical Industry Ecology - Toxicology and Information Center.

Johnson, B.L. and C.T. De Rosa. 1999. Public Health Implications. Environmental Research. 80(Supplement)246-248.

Johnson, B.L., H.E. Hicks, D.E. Jones, W. Cibulas, and C.T. DeRosa, 1998. Public health implications of persistent toxic substances in the Great Lakes and St. Lawrence Basins. J. Great Lakes Research, 24:698-722.

Julien, G., J.D. Baxter, M. Crago, H.J. Ilecki and F. Therien, 1987. Chronic otitis media and hearing deficit among native children of Kuujjuaraapik (Northern Quebec): A pilot project. Canadian Journal of Public Health. 78:57-61.

Lakewide Management Plan for Lake Ontario, 1998. Stage 1: Definition. 88 pp. & 7 appendices.

Lonky, E., J. Reihman, T. Darvill, J. Mather, Sr., and H. Daly, 1996. Neonatal behavioral assessment scale performance in humans influenced by maternal consumption of environmentally contaminated Lake Ontario fish. Journal of Great Lakes Research, 22(2):198-212.

Mendola, P. G.M. Buck, L.E. Sever, M. Zielezny and J.E. Vena, 1997. Consumption of PCB-contaminated freshwater fish and shortened menstrual cycle length. American Journal of Epidemiology. 146:955-960.

Moysich, K.B., P.G. Shields, J.L. Freudenheim, E.M. Schisterman, J.E. Vena, P. Kostyniak, H. Greizerstein, J. Marshall, S. Graham, and C.B. Ambrosone, 1999. Polychlorinated biphenyls, cytochrome P4501A1 polymorphism, and postmenstrual breast cancer risk. Cancer Epidemiology, Biomarkers and Prevention. 8:41-44.

Munk, Walter and Carl Wunsch, 1982. Observing the ocean in the 1990s. Royal Society of London. Philosophical Transactions, Series A, Vol. 307. pp. 439-464.

National Oceanographic Partnership Program Office, 1999. Final Report to Congress: "Toward a U.S. Plan for an Integrated Sustained Ocean Observing System." NOPP, Washington, DC. http://core.cast.msstate.edu/NOPPpg1.html

National Research Council of the United States and The Royal Society of Canada, 1985. The Great Lakes Water Quality Agreement: An evolving instrument for ecosystem management. National Academy Press, Washington, DC. 224 pp.

Needleman, H.L., and C.A. Gatsonis, 1990. Low-level lead exposure and the I.Q. of children. Journal of the American Medical Association, 263:673-678.

Oakley, K., 1979. Review of the Changes in the 1978 Great Lakes Water Quality Agreement. International Joint Commission. 21 pp.

Organization for Economic Co-operation and Development, 1997. Draft Detailed Review Paper: Appraisal of Test Methods for Sex-Hormone Disrupting Chemicals. OECD, Paris.

Peierls, B.L., N.F. Caraco, M.L. Pace, and J.J. Cole, 1991. Human influence on river nitrogen. Nature, 350.

Pekarik, C., and D.V. Weseloh, 1998. Organochlorine contaminants in herring gull eggs from the Great Lakes 1974-1995: Change point regression analysis and short-term regression. In: Trends in Levels and Effects of Persistent Toxic Substances in the Great Lakes. Michael Gilbertson, Glen A. Fox, and William W. Bowerman (Eds.). Environmental Monitoring and Assessment, 53:77-115.

Peterson, R.E., R.W. Moore, T.A. Mably, D.J. Bjerke and R.W. Goy, 1992. Male reproductive system ontogeny: Effects of perinatal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. In: Colborn, T. and C. Clement (eds.). Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Advances in Modern Environmental Toxicology. Princeton Scientific Publishing, Princeton, New Jersey. 403 pp.

Porter, W.P., J.W. Jaeger, and I.H. Carlson, 1999. Endocrine, immune, and behavioral effects of aldicarb (carbamate), atrazine (triazine) and nitrate (fertilizer) mixtures at ground water concentrations. Toxicology and Industrial Health, 15:133-150.

Province of Ontario, 1999. Guide to Eating Ontario Sport Fish, 1999-2000. Queen's Printer, Ottawa. ISSN 0826-9653. 197 pp.

Reiter, L.W., C. DeRosa, R.J. Kavlock, G. Lucier, M.J. Mac, J. Melillo, R. Melnick, T. Sinks and B.T. Walton, 1998. The U.S. Federal framework for research on endocrine disruptors and an analysis of research programs supported during Fiscal Year 1996. Environmental Health Perspectives. 106:105-113.

Rouse, J.D., C.A. Bishop, and J. Struger, 1999. Surface water quality has important ecological implications for amphibian survival. Poster Report, Environment Canada, Canadian Wildlife Service and Ecosystem Health Division, Box 5050, Burlington, Ont.

Scientific Committee on Toxicity, Ecotoxicity and the Environment, 1999. CSTEE Opinion on Human and Wildlife Health Effects of Endocrine Disrupting Chemicals, with Emphasis on Wildlife and on Ecotoxicology Test Methods. DG XXIV, Consumer Policy and Consumer Health Protection, European Commission. 96 pp.

Servos, M.R., J.L. Parrott, J.P. Sherry and S.B. Brown, 1999. Developing biological endpoints for defining virtual elimination: A case study for PCDDs and PCDFs. Water Quality Res. J Canada, Vol. 34, No. 3, pp. 391-422.

Sparks, R.E., and F.S. Dillon, 1993. Illinois River Fingernail Clam Toxicity Study. Final Report to Illinois Department of Conservation. Report F-94-R, Illinois Natural History Survey, Havana, IL.

Sprunt, A. IV, W.B. Robertson, Jr., S. Postupalsky, R.J. Hensel, C.E. Knoder and F.J. Ligas, 1973. Comparative productivity of six bald eagle populations. Transactions of the North American Wildlife Resources Conference. 38:96-106.

Tilden, J., L.P. Hanrahan, H. Anderson, C. Palit, J. Olson, W. MacKenzie, and the Great Lakes Sport Fish Consortium, 1997. Health advisories for consumers of Great Lakes sport fish: Is the message being received? Environmental Health Perspectives, 105:1360-1365.

U.S. EPA, 1998. Endocrine Disruptor Screening Program. Federal Register. 63:42852-5.

U.S. EPA, 1997. Special Report on Environmental Endocrine Disruption: An Effects Assessment and Analysis. EPA/630/R-96/012.

U.S. EPA SAB (U.S. Environmental Protection Agency Science Advisory Board), 1995a. Beyond the Horizon: Using Foresight to Protect the Environmental Future. EPA-SAB-EC-95-007. (January 1995) 34 pp.

U.S. EPA SAB (U.S. Environmental Protection Agency Science Advisory Board), 1995b. Beyond the Horizon: Using Foresight to Protect the Environmental Future. A Technical Annex, SAB Report: Futures, Methods and Issues, EPA-SAB-EC-95-007A. 80 pp.

U.S. EPA, 1992. Framework for ecological risk assessment. Risk Assessment Forum, Washington, DC EPA/630/R-92/001. 56 pp.

U.S. EPA, 1986. Quality Criteria for Water. EPA 440/5-86-001, Washington, DC.

U.S. EPA and NYSDEC. 1997, Reduction of Toxics Loadings to the Niagara River from Hazardous Waste Sites in the United States. 71 pp.

U.S. Executive Order 13084, Presidential Document May 14, 1998

Van den Berg, M. et al., 1998. Toxic Equivalency Factors (TEFs) for PCBs, PCDDs, PCDFs for Humans and Wildlife. Environmental Health Perspectives, 106:775-792.

Voccia. I., B. Blakley, P. Brousseau, and M. Fournier, 1999. Immunotoxicity of pesticides: a review. Toxicology and Industrial Health, 15:119-132.

vom Saal, F.S., S.C. Nagel, P. Palanza, M. Boechler, S. Parmigiani, and W.V. Welshons, 1995. Estrogenic pesticides: Binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice. Toxicology Letters. 77:343-350.

Weisglas-Kuperus, N., T.C.S. Sas, C. Koopman-Esseboom, C.W. Van Der Zwan, M.A.J. De Ridder, A. Beishuizen, H. Hooijkaas and P.J.J. Sauer, 1995. Immunological effects of background prenatal and postnatal exposure to dioxins and polychlorinated biphenyls in Dutch infants. Pediatric Research. 38:404-410.

Weiss, B., 1997. Endocrine disruptors and sexually dimorphic behaviors: A question of heads and tails. NeuroToxicology. 18:581-586.

Welshons, W.V., S.C. Nagel, K.A. Thayer, B.M. Judy and F.S. vom Saal, 1999. Low-dose bioactivity of xenoestrogens in animals: fetal exposure to low doses of methoxychlor and other xenestrogens increases adult prostate size in mice. Toxicology and Industrial Health. 15:12-25.

World Commission on Environment and Development, 1987. Our Common Future. Oxford University Press, Oxford, New York. 398 pp.